Disease: Crohn's disease of large bowel
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SLC11A1 P49279 solute carrier family 11 member 1 Transporter 1.5E-19 0.525 0.846
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NKX2-3 Q8TAU0 NK2 homeobox 3 Transcription factor 0.95 0.716 0.231
NFKBIA P25963 NFKB inhibitor alpha 0.99 0.487 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
IRGM A1A4Y4 immunity related GTPase M 0.617 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
GUCY2C P25092 guanylate cyclase 2C Kinase 1.4E-30 0.599 0.577
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731